Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 6;37(45):5926–5938. doi: 10.1038/s41388-018-0394-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Interference with HMGA1 inhibits cell proliferation, induces cell death, and impairs in vitro motility and invasion of SW872 liposarcoma cells. a Total cell lysates from SW872 cells were analyzed 24 an 48 h upon depletion for the expression of HMGA1, PARP, and Hsp70. Cell viability was evaluated by Trypan blue exclusion from three independent experiments (P < 0.001). b Apoptosis was evaluated by Annexin-V/PI flow cytometric assay. Cell death was presented as the means ± SD of triplicate experiments (P < 0.01). c Chemotaxis and chemoinvasion assays were performed to examine the effect of HMGA1 depletion on SW872 cells. Number of migrated and invading cells was presented as the means ± SD of triplicate experiments of each group (P < 0.0001)