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. 2018 Nov 8;9:4680. doi: 10.1038/s41467-018-06861-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Enrichment of deregulated genes in BRL3ox root vasculature. a Tissue enrichment for upregulated (red) or downregulated (blue) genes in control conditions. Bars trespassing the p-value threshold (0.05) were considered enriched in the dataset. b Tissue enrichment for genes affected by the interaction genotype*drought. Bars trespassing the threshold p-value < 0.05 were considered enriched in the dataset. a, b Deregulated genes tissue enrichment. AGL42: quiescent center, APL: phloem + companion cells, COBL9: root hair cells, CORTEX: cortex, GL2: non-hair cells, J2661: pericycle, JO121: xylem pole pericycle, LRC: lateral root cap, PET111: columella, RM1000: lateral root primordia, S17: phloem pole pericycle, S18: maturing Xylem, S32: protophloem, S4: developing xylem, SCR5: endodermis, and SUC2: phloem. y-axis represent the negative logarithm of one-tailed Fisher’s test. c Deregulated genes enriched in the Pericycle (J2261 marker). d Deregulated genes enriched in the Phloem Pole Pericycle (S17 marker). c, d Bars represent the log₂-fold-change of BRL3ox vs. WT roots in control (black) or the difference of drought responses between BRL3ox and WT (FC drought/CTRL in BRL3ox—FC drought/CTRL in WT) in the lineal model (gray). Blue boxes highlight enzymes directly involved in the metabolism of deregulated metabolites