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. 2018 Nov 8;8:16533. doi: 10.1038/s41598-018-34913-7

Table 5.

OR and 95% CI of GGT ≥75th associated with major CRFs and clustered risk factors. Age, UA, alcohol, ethnicity, and all other risk factors were adjusted when estimating odds ratios (ORs) with 95% confidence intervals (CIs) of each variable.

CRFs Men Women
Unadjusted OR (95% CI) GGT ≥75th Adjusted OR (95% CI) GGT ≥75th Unadjusted OR (95% CI) GGT ≥75th Adjusted OR (95% CI) GGT ≥75th
Dyslipidemia 4.530 (4.084–5.025)* 3.895 (3.487–4.352)* 3.439 (3.157–3.745)* 2.187 (1.985–2.408)*
Hypertension1 1.999 (1.820–2.195)* 1.709 (1.536–1.901)* 2.498 (2.280–2.738)* 1.483 (1.334–1.649)*
Hypertension2 2.515 (2.294–2.757)* 2.122 (1.920–2.344)* 2.251 (2.074–2.445)* 1.681 (1.537–1.839)*
Diabetes 2.365 (1.977–2.830)* 2.573 (2.1100–3.138)* 4.952 (4.076–6.016)* 2.904 (2.349–3,591)*
Current smoking 1.573 (1.439–1.720)* 1.325 (1.201–1.462)* 1.815 (1.452–2.267)* 1.365 (1.069–1.745)*
Overweight 3.739 (3.412–4.096)* 3.165 (2.859–3.504)* 3.219 (2.953–3.508)* 2.086 (1.896–2.295)*
clustered risk factors
   0 1 (ref) 1 (ref) 1 (ref) 1 (ref)
   1 2.334 (1.892–2.878)* 2.096 (1.685–2.606)* 2.804 (2.498–3.148)* 2.087 (1.841–2.366)*
   2 6.026 (4.936–7.356)* 4.853 (3.923–6.002)* 5.702 (5.052–6.437)* 3.412 (2.968–3.921)*
   ≥3 13.859 (11.360–16.907)* 10.843 (8.748–13.441)* 10.415 (9.013–12.036)* 5.344 (4.516–6.324)*

*P < 0.05.

1OR and 95% CI of GGT ≥75th associated with hypertension defined with JNC7.

2OR and 95% CI of GGT ≥75th associated with hypertension defined with 2017 ACC/AHA.