Table 5.
OR and 95% CI of GGT ≥75th associated with major CRFs and clustered risk factors. Age, UA, alcohol, ethnicity, and all other risk factors were adjusted when estimating odds ratios (ORs) with 95% confidence intervals (CIs) of each variable.
| CRFs | Men | Women | ||
|---|---|---|---|---|
| Unadjusted OR (95% CI) GGT ≥75th | Adjusted OR (95% CI) GGT ≥75th | Unadjusted OR (95% CI) GGT ≥75th | Adjusted OR (95% CI) GGT ≥75th | |
| Dyslipidemia | 4.530 (4.084–5.025)* | 3.895 (3.487–4.352)* | 3.439 (3.157–3.745)* | 2.187 (1.985–2.408)* |
| Hypertension1 | 1.999 (1.820–2.195)* | 1.709 (1.536–1.901)* | 2.498 (2.280–2.738)* | 1.483 (1.334–1.649)* |
| Hypertension2 | 2.515 (2.294–2.757)* | 2.122 (1.920–2.344)* | 2.251 (2.074–2.445)* | 1.681 (1.537–1.839)* |
| Diabetes | 2.365 (1.977–2.830)* | 2.573 (2.1100–3.138)* | 4.952 (4.076–6.016)* | 2.904 (2.349–3,591)* |
| Current smoking | 1.573 (1.439–1.720)* | 1.325 (1.201–1.462)* | 1.815 (1.452–2.267)* | 1.365 (1.069–1.745)* |
| Overweight | 3.739 (3.412–4.096)* | 3.165 (2.859–3.504)* | 3.219 (2.953–3.508)* | 2.086 (1.896–2.295)* |
| clustered risk factors | ||||
| 0 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| 1 | 2.334 (1.892–2.878)* | 2.096 (1.685–2.606)* | 2.804 (2.498–3.148)* | 2.087 (1.841–2.366)* |
| 2 | 6.026 (4.936–7.356)* | 4.853 (3.923–6.002)* | 5.702 (5.052–6.437)* | 3.412 (2.968–3.921)* |
| ≥3 | 13.859 (11.360–16.907)* | 10.843 (8.748–13.441)* | 10.415 (9.013–12.036)* | 5.344 (4.516–6.324)* |
*P < 0.05.
1OR and 95% CI of GGT ≥75th associated with hypertension defined with JNC7.
2OR and 95% CI of GGT ≥75th associated with hypertension defined with 2017 ACC/AHA.