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. 2018 Nov 8;8:16534. doi: 10.1038/s41598-018-34724-w

Table 1.

Modifications of the coding sequence of the iPBase gene to generate the hyPBaseapis gene.

Hyperactivation24 7 codons (I30V [GTA], S103P [CCA], G165S [TCT], M282V [GTG], S509G [GGA], N538K [AAA], N570S [TCT])
Codon-optimization 24 nucleotides (C81T, G264A, G315A, C378A, C390T, C409T, G480A, G696A, C699A, G786A, G831A, G843A, C1128A, C1158A, G1164A, C1200A, C1345T, C1350T, G1380A, G1392A, C1497A, C1587A, C1689A, G1701A)