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. 2018 Nov 2;9:1254. doi: 10.3389/fphar.2018.01254

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Copyright © 2018 Hsiao, Huang and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of the thermal stability of freely dissolved ICG and RIPND-entrapped ICG. (I) UV-Vis spectra of freely dissolved ICG in DI water (A,B) and RIPND-entrapped ICG (C,D) under 4 (A,C) and 37°C (B,D) without light exposure for 0, 12, 24, and 48 h. The absorbance at λ = 780 nm indicates the amount of ICG remaining in each sample at the time of measurement. (II) Quantitative analyses of residual ICG in the matrix under 4 or 37°C within 48 h. Values are mean ± s.d. (n = 3). ^∗P < 0.05.