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. 2018 Jul 16;32(11):1752–1759. doi: 10.1038/s41433-018-0151-y

Table 3.

Clinical details of children and binocular outcomes (reporting unit: children)

Reporting unit: children Laser Anti-VEGF antibody
APROP, N = 8 Type 1, N = 96 Type 2 plus, N = 39 Type 2, N = 6 Mild, N = 2 Partial retinal detachment, N = 2 Total, N = 153 APROP, N = 2 Type 1, N = 11 Type 2 plus, N = 1 Total, N = 14
Gestational age at birth, median (IQR) 25.1 (24.3–25.9) 25.1 (24.4–26) 25.3 (24.4–26.4) 25.2 (24.7–26.6) 26.1 (25.9–26.3) 24.4 (24–24.7) 25.1 (24.4–26) 24.9 (24.4–25.4) 24.9 (23.7–25.9) 27.6 25.1 (24.3–25.9)
Birth weight (g), median (IQR) 680 (630–840) 715 (641–824) 740 (660–830) 721 (670–850) 781 (752–810) 622 (610–634) 716 (642–830) 723 (655–790) 590 (565–710) 780 625 (585–757)
Proportion of female children, n (%) 4 (50) 45 (46.9) 15 (38.5) 3 (50) 1 (50) 1 (50) 69 (45.1) 1 (50) 6 (54.6) 0 7 (50)
Age at first treatment (days), median (IQR) 70 (63–73) 83 (73–97) 78 (68–92), n = 38 85 (83–93) 137 (111–163) 82 (80–83) 81 (7196), n=152 74 (71–76) 73 (66–80) 64 72 (66–80)
Age at follow-up visit (years), median (IQR) 1.5 (1.2–1.6) n = 5 1.1 (1.0–1.4), n = 84 1.2 (1.0–1.5), n = 36 1.3 (1.1–1.9), n = 5 1.4 (1.4–1.5) 1.2, n = 1 1.2 (1.0–1.5), n=133 1.0, n = 1 1.2 (0.9–1.5), n = 9 1.2 1.2 (0.9–1.5), n=11
Children with anisometropia of 1 D or more, n (%) 1 (25) n = 4 12 (17.7), n = 68 6 (22.2), n = 27 0, n = 3 1 (50) 0, n = 1 20 (19), n=105 0, n = 1 5 (62.5), n = 8 0 5 (50), n=10
Anisometropia, median (IQR), n (%) 0.5 (0.31–0.75) n = 4 0.25 (0–0.69), n = 68 0 (0–0.5), n = 27 0 (0–0.63), n = 3 1 (0–2) 0, n = 1 0.13 (0–0.63), n=105 0, n = 1 1 (0.13–1.75), n = 8 0 0.63 (0–1.25), n=10
Glasses prescribed, n (%) 2 (50) n = 4 15 (21.1), n = 71 3 (12), n = 25 0, n = 5 0, n = 1 1 (100), n = 1 21 (19.6), n=107 0, n = 1 3 (42.9), n = 7 0 3 (33.3), n=9
Manifest strabismus, n (%) 2 (40), n = 5 15 (18.1), n = 83 6 (16.2), n = 37 1 (20), n = 5 0, n = 2 1 (100), n = 1 25 (18.8), n=133 0, n = 1 2 (22.2), n = 9 0 2 (18.2), n=11
Nystagmus 2 8 1 1 12 1 1