Table 1.
Ratio of receptor–ligand binding site areas
| TNFRSF complex | PDB code | Receptor chain | Ligand chain | BSA (Å2) | Adjacent ligand chain | BSA (Å2) | Ratio of site 1 to site 2 |
|---|---|---|---|---|---|---|---|
| 4-1BB+4-1BBL | X | A | 808 | C | 138 | 5.86:1 | |
| 4-1BB+4-1BBL | 6MGP | Y | B | 827 | A | 114 | 7.25:1 |
| 4-1BB+4-1BBL | Z | C | 833 | B | 112 | 7.43:1 | |
| CD40+CD154 | 3QD6 | R | B | 648 | C | 339 | 1.91:1 |
| FasL+DcR3 | 4MSV | B | A | 472 | Aa | 460 | 1.02:1 |
| LIGHT+DcR3 | 4J6G | D | B | 545 | Ba | 464 | 1.17:1 |
| TNFα+TNFR2 | 3ALQ | R | A | 716 | B | 619 | 1.16:1 |
| OX40+OX40L | 2HEV | R | Fa | 583 | F | 447 | 1.30:1 |
| TNFβ+TNFR1 | 1TNR | R | A | 599 | Aa | 518 | 1.16:1 |
| LTβ+LTβR | 4MXW | R | B | 490 | D | 332 | 1.48:1 |
a denotes chain generated by symmetry operator