Fig. 4.

Voxel-by-voxel analysis of V_T in AD versus HC. [¹¹C]LY2795050 V_T images from a two-sample t-test between AD and HC using statistical parametric mapping (SPM) overlayed with an atlas. Regions with a significant difference (p < 0.001, family-wise error [FWE]) between AD and HC, where HC > AD, are outlined as follows: a frontal cortex, and b Location of the coronal slice shown in the sagittal view of the brain—white line indicates location of coronal slice A in sagittal plane. a Coordinates are (x = 57.0, y = −4.0, z = −2.0). Colored legend depicts t-scores ranging from 0 to 5