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. 2018 Sep 28;115(39):646–652. doi: 10.3238/arztebl.2018.0646

Table 2. TNM classification of penile carcinomas of the Union Internationale Contre le Cancer (UICC) (32).

Primary tumor (T) Tis Carcinoma in situ
Ta Non-invasive localized verrucous carcinoma
T1 Tumor invades subepithelial connective tissue
T1a Without lymphovascular invasion and well differentiated
T1b With lymphovascular invasion or poorly differentiated
T2 Tumor invades corpus spongiosum with or without invasion of the urethra
T3 Tumor invades corpus cavernosum without or with invasion of the urethra
T4 Tumor invades other adjacent structures
Regional lymph nodes (N) (clinical) N0 No palpable or visibly enlarged inguinal lymph nodes
N1 Palpable mobile unilateral lymph node
N2 Palpable mobile multiple or bilateral inguinal lymph nodes
N3 Fixed inguinal nodal mass or pelvic lymphadenopathy, unilateral or bilateral
Regional lymph nodes (pN) (pathological) pN0 No regional lymph node metastasis
pN1 Metastasis in up to two regional lymph nodes
pN2 Metastases in three or more unilateral lymph nodes or bilateral inguinal lymph nodes
pN3 Metastasis in pelvic lymph nodes, unilateral or bilateral, or extranodal extension of any regional lymph node metastasis
Distant metastasis (M) M0 No distant metastasis
M1 Distant metastasis