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. 2018 Nov 8;8:16515. doi: 10.1038/s41598-018-34970-y

Figure 3.

Figure 3

Inulin adversely affected the liver by manifestations of hepatic inflammation Mice were fed a WTD containing 0.5% cholesterol ± inulin for 11 weeks. (A) Liver weight, (B) liver morphology, (C) hepatocyte size as a marker for hepatic hypertrophy, (D) microvesicular and macrovesicular steatosis, (E) liver TG content, (F) qRT-PCR analysis of F4/80, Mcp-1, Tnf-α, IL-6, IL-10, and (G) immunohistochemical analysis of hepatic F4/80 were determined. Values are presented as means ± SEM (n = 10 mice per group). *P < 0.05, **P < 0.01, ***P < 0.001 vs. control.