Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 8;8:16549. doi: 10.1038/s41598-018-34812-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Verification of previously identified SNPs and location of new SNPs that differ between the virulent VL and attenuated CL strains of L. donovani. Chromosomal location of previously identified homozygous non-synonymous SNPs between the cutaneous and visceral disease derived L. donovani strains (Red)⁴ compared to the novel SNPs identified only in this study (Blue) (synonymous and heterozygous codon changes identified are not labeled). Note that all the previously identified SNPs were also identified, or confirmed, in this study. 70 SNPs were previously identified across 66 genes. The same 70 SNPs were identified in this study, with an additional 15 novel SNPs not previously seen specific to the cutaneous strain. Genomic locations of SNPs identified in the previous study were translated to new genomic coordinates based on the new assembly for consistency. Arrows in yellow highlight the position of the previously identified RagC SNP on chromosome 36 and the A2 copy number difference on chromosome 22.