REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse anti Thymine Dimer clone KTM53	Kamiya	Cat#MC-062; RRID: AB_1233355
Rabbit anti CDK2 clone M2	Santa Cruz	Cat#SC-163; RRID: AB_631215
Mouse anti Tyrosinase clone T311	Santa Cruz	Cat#SC-20035; RRID: AB_628420
Mouse anti MITF clone C5	Laboratory of David Fisher	N/A
Rabbit anti pCREB (Ser133)	Cell signaling	Cat#9191; RRID: AB_331606
Mouse anti actin clone C4	Santa Cruz	Cat#sc-47778; RRID: AB_2714189
Rabbit anti Ki-67 clone D3B5	Cell signaling	Cat#11882S; RRID: AB_2687824
Mouse anti CDK2 clone 2D9	LSBio	Cat#C337371; RRID: AB_2728767
Rabbit anti CDK2 clone E304	Abcam	Cat#ab32147; RRID: AB_726775
Mouse anti HMB45 + M2-7C10 + M2-9E3	Abcam	Cat#ab732; RRID: AB_305844
Mouse anti β-tubulin	Sigma-Aldrich	Cat#T4026; RRID: AB_477577
Rabbit anti H3K4me3	Laboratory of David Fisher	N/A
Rabbit Anti-Histone H3 (phospho S10)	Abcam	Cat#ab5176; RRID: AB_304763
Donkey anti mouse Alexa 488-conjugated secondary antibody	Life Technologies	Cat# A-11008; RRID: AB_143165
Goat anti rabbit Alexa-594-conjugated secondary antibody	Life Technologies	Cat# A-21203; RRID: AB_141633
Biological Samples
Human skin	Resected remnant skin from Wolfson Medical Center	approved Helsinki (0015-16-WOMC)
Chemicals, Peptides, and Recombinant Proteins
Forskolin	Sigma-Aldrich	F6886-10MG
FM19G11	Sigma-Aldrich	F8807-5MG
VECTASHIELD Antifade Mounting Medium with DAPI	Vector	H-1200
Fluoroshield with DAPI	Sigma-Aldrich	F6057
Deposited Data
Original imaging data in Mendeley Data	This paper	https://dx.doi.org/10.17632/jsmb8ymk94.1
Gene-expression profiling of MNT-1 melanoma line upon treatment with cAMP	This paper	GEO: GSE114764
Experimental Models: Cell Lines
Human: MNT-1	Laboratory of Vincent J. Hearing; Virador et al., 2001.	RRID: CVCL_5624
Human: WM3682	Laboratory of Levi A. Garraway; Golan et al., 2015	RRID: CVCL_AP78
Human: WM3526	Laboratory of Levi A. Garraway; Golan et al., 2015	N/A
Human: WM3314	Laboratory of Levi A. Garraway; Golan et al., 2015	N/A
Human: 451LU	Laboratory of Levi A. Garraway; Golan et al., 2015	RRID: CVCL_6357
Human: A375	Laboratory of Levi A. Garraway; Golan et al., 2015	RRID: CVCL_0132
Human: WM1716	Laboratory of Levi A. Garraway; Golan et al., 2015	RRID: CVCL_AP82
Experimental Models: Organisms/Strains
Mouse: C57BL/6	Harlan Laboratories	Cat#1BL/626
Oligonucleotides
siMITF	Ambion	Cat#AM16204
Mimic miR-148a	Ambion	ID: MC10263 Cat#4464066
Mimic miR-101	Ambion	ID: MC11414
Mimic miR-216a	Ambion	ID: MC24316
Mimic miR-506	Ambion	ID: MC10709
Mimic miR-25	Ambion	ID: MC12401
Mimic miR-124	Ambion	ID: MC11154
Mimic miR-340	Ambion	ID: MC12670
SiControl	Ambion	ID: AM4635
Sequences of all oligonucleotides are detailed in Table S5.	This paper	N/A
Recombinant DNA
PGL4.11-148a promoter-Luciferase-clone 1	This paper	N/A
3′ UTR MITF Luciferase reporter	GeneCopoeia	N/A
pcDNA MITF expression plasmid	Laboratory of David Fisher	N/A
Software and Algorithms
MATLAB R2017B	MathWorks	https://www.mathworks.com/
R3.4.3	CRAN	https://cran.r-project.org/