Table 2.
Hemodialysis characteristics of the study population
| Control n = 12 |
ID-HTN n = 10 |
P value | |
|---|---|---|---|
| Dialysis vintage, yr | 6.0 ± 1.3 | 3.1 ± 0.5 | 0.072 |
| Access, n (%) | |||
| AV fistula | 7 (58) | 6 (60) | 0.937 |
| AV graft | 4 (33) | 4 (40) | 0.746 |
| Catheter | 1 (8) | 0 (0) | 0.350 |
| HD hemodynamicsa | |||
| Pre-HD SBP, mm Hg | 148 ± 3 | 178 ± 3 | <0.001 |
| Post-HD SBP, mm Hg | 130 ± 2 | 154 ± 3 | <0.001 |
| Nadir HD SBP, mm Hg | 111 ± 3 | 145 ± 3 | <0.001 |
| Pre-HD DBP, mm Hg | 81 ± 2 | 97 ± 3 | <0.001 |
| Post-HD DBP, mm Hg | 72 ± 2 | 98 ± 14 | <0.001 |
| Nadir HD DBP, mm Hg | 61 ± 2 | 79 ± 2 | <0.001 |
| Pre-HD HR, bpm | 83 ± 2 | 79 ± 3 | 0.334 |
| Post-HD HR, bpm | 82 ± 2 | 84 ± 2 | 0.411 |
| HD characteristicsa | |||
| Interdialytic weight gain, kg | 2.2 ± 0.2 | 2.8 ± 0.2 | 0.039 |
| Dialysis time, min | 223 ± 8 | 223 ± 8 | 0.958 |
| Ultrafiltration volume, L | 2.6 ± 0.1 | 2.9 ± 0.2 | 0.096 |
| Ultrafiltration rate, ml/kg per hr | 8.1 ± 0.4 | 8.5 ± 0.5 | 0.594 |
| Laboratory measures | |||
| Sodium, mEq/l | 138.1 ± 0.9 | 138.3 ± 0.6 | 0.848 |
| Potassium, mEq/l | 4.5 ± 0.1 | 4.8 ± 0.3 | 0.346 |
| Hemoglobin, g/dl | 11.0 ± 0.2 | 11.3 ± 0.5 | 0.600 |
| Phosphorus, mEq/l | 6.2 ± 0.4 | 6.3 ± 0.8 | 0.905 |
| Parathyroid hormone, pg/ml | 810 ± 186 | 598 ± 126 | 0.359 |
| Kt/V | 1.63 ± 0.08 | 1.41 ± 0.11 | 0.110 |
| Urea reduction ratio, % | 75.1 ± 1.7 | 69.2 ± 3.4 | 0.133 |
AV, arteriovenous; DBP, diastolic blood pressure; HD, hemodialysis; HR, heart rate; Kt/V, measure of dialysis adequacy (K = dialyzer clearance of urea, t = dialysis time, V = volume of distribution of urea, which is roughly total body water), SBP, systolic blood pressure.
Values with plus/minus sign are the mean ± SE. Bold indicates statistically significant P values < 0.05.
a
Mean values averaged across 6 consecutive HD treatments.