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. 2018 Aug 3;3(6):1373–1384. doi: 10.1016/j.ekir.2018.07.021

Table 4.

Immunosuppression use, by diagnosis and agea

Pediatric
P value Adult
P value
IgAN n = 173
IgAV n = 112
IgAN n = 333
IgAV n = 49
n (%) n (%) n (%) n (%)
Number of medications usedb
 0 85 (49.7%) 27 (24.1%) <0.001 147 (44.1%) 6 (12.2%) <0.001
 1 44 (25.7%) 44 (39.3%) 125 (37.5%) 27 (55.1%)
 2 34 (19.9%) 37 (33.0%) 43 (12.9%) 12 (24.5%)
 3 8 (4.7%) 2 (1.8%) 15 (4.5%) 3 (6.1%)
 4 0 (0.0%) 0 (0.0%) 3 (0.9%) 1 (2.0%)
Medication class
 Cyclophosphamide 7 (4.0%) 9 (8.0%) 0.16 15 (4.5%) 8 (16.3%) 0.001
 Azathioprine 9 (5.2%) 10 (8.9%) 0.23 13 (3.9%) 3 (6.1%) 0.47
 Mycophenolate mofetil 25 (14.5%) 23 (20.5%) 0.19 36 (10.8%) 5 (10.2%) 0.90
 Corticosteroids 80 (46.2%) 82 (73.2%) <0.001 177 (53.2%) 42 (85.7%) <0.001
 RAAS blockade 116 (67.1%) 70 (62.5%) 0.36 295 (88.6%) 43 (87.8%) 0.86
a

Immunosuppression use at or before enrollment visit.

b

Missing medication data for 2 patients.