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. 2018 Sep 20;115(9):1826–1835. doi: 10.1016/j.bpj.2018.09.010

Table 1.

Key Parameters Used in Our Simulations

Physical meaning Symbol Value Reference Normalization
Formula Value
Cell area stiffness Ka 105–107 N ⋅ m−3 (5, 60) ND ND
Cell reference area A0 900 μm2 Assumed ND ND
Cell contractile modulus Kc 10−5–10−4 N ⋅ m−1 (61) Kc/(KaA0) 0.01–0.1
Cell-cell interfacial tension Λ 10−9–10−8 N (62) Λ/(KaA03/2) 0.01–0.1
Friction coefficient γ 0.01–0.1 N ⋅ s ⋅ m−1 (62) ND ND
Length scale 30 μm =A0 ND ND
Time scale τ 100 s τ=γ/(KaA0) ND ND
Self-propelled velocity v0 10−8 ∼ 10−7 m ⋅ s−1 (63) v0τ/A0 0.01–0.1
LA intensity μa ∼10−4 s−1 Assumed μaτ ∼0.1
CIL intensity μc ∼10−3 s−1 Assumed μcτ ∼1.0

ND, no data.