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. 2018 Jun 30;3(6):1434–1442. doi: 10.1016/j.ekir.2018.06.007

Table 3.

Odds ratios associated with a 1-unit increment in log(uPl/Cr)

Odds ratio (95% CI) P
2-yr BP increasea,b,c
 Univariate 2.30 (0.97−5.43) 0.06

Hazard ratio (95% CI) P

25-yr Incident hypertension
 Univariate 2.05 (1.33−3.17) 0.001
 Model 1 (adjusted for T1D duration, DBP)a 2.18 (1.37−3.48) 0.001
 Model 2 (adjusted for T1D duration, uAlb/Cr, DBP)b 1.15 (0.59−2.24) 0.7
All-cause mortality
 Univariate 1.97 (1.17−3.39) 0.01
 Model 1 (adjusted for T1D duration)a 1.93 (1.15−3.24) 0.01
 Model 2 (adjusted for uAlb/Cr)b 0.93 (0.43−2.00) 0.9
Cardiovascular mortalitya,b,c
 Univariate 3.30 (1.43−7.63) 0.005

BP, blood pressure; CI, confidence interval; DBP, diastolic blood pressure; log(uPl/Cr), log of the urinary plasmin(ogen)/creatinine; SBP, systolic blood pressure; T1D, type I diabetes mellitus; uAlb/Cr, urinary albumin/creatinine.

a

Variables offered for adjustment were duration of diabetes, sex, body mass index, SBP and DBP, and estimated glomerular filtration rate. Only those listed in parentheses were retained after backward selection.

b

Same variables offered as in model 1 with the addition of uAlb/Cr. Only those listed in parentheses were retained after backward selection.

c

Only log(uPl/Cr) was retained after backward selection.