Table 4.
Early Changes (Week 3) in Analyte Levels
| Analyte | Mean Log Difference Visit 2 and 1 Mean ± SEM |
P | q |
|---|---|---|---|
| PARC | −0.31 ± 0.03 | < .001 | < 0.001 |
| MMP9 total | −0.17 ± 0.02 | < .001 | < 0.001 |
| Resistin | −0.29 ± 0.04 | < .001 | < 0.001 |
| SPD | −0.18 ± 0.02 | < .001 | < 0.001 |
| Eotaxin 2 | −0.15 ± 0.02 | < .001 | 0.001 |
| TIE 2 | −0.19 ± 0.03 | < .001 | 0.002 |
| SDF1 | 0.08 ± 0.01 | < .001 | 0.002 |
| Periostin | 0.10 ± 0.02 | < .001 | 0.002 |
| MCP2 | −0.14 ± 0.02 | < .001 | 0.002 |
| TATI | −0.11 ± 0.02 | < .001 | 0.002 |
| IL-18 | −0.16 ± 0.03 | < .001 | 0.004 |
| MIP1 beta | −0.28 ± 0.05 | < .001 | 0.004 |
| NGAL | −0.17 ± 0.03 | < .001 | 0.004 |
| Tumor necrosis factor ligand superfamily member 12 (Tweak) | 0.09 ± 0.02 | < .001 | 0.004 |
| TRAIL R3 | −0.18 ± 0.03 | < .001 | 0.004 |
| ENA 78 | −0.17 ± 0.03 | < .001 | 0.004 |
| Angiopoietin 1 | −0.14 ± 0.03 | < .001 | 0.004 |
| CD5L | −0.13 ± 0.03 | < .001 | 0.004 |
| Protein S100 A6 | −0.21 ± 0.05 | < .001 | 0.009 |
| CCL15 | −0.08 ± 0.02 | < .001 | 0.01 |
| GDF15 | −0.12 ± 0.03 | .001 | 0.01 |
| CEA | 0.10 ± 0.02 | .001 | 0.01 |
| TARC | 0.14 ± 0.03 | .002 | 0.01 |
| VEGF-D | −0.10 ± 0.02 | .002 | 0.02 |
| Haptoglobin | 0.14 ± 0.03 | .002 | 0.02 |
| EN-RAGE | −0.31 ± 0.08 | .002 | 0.02 |
| Fibulin 1C | 0.16 ± 0.04 | .002 | 0.02 |
| Lactoferrin | −0.23 ± 0.06 | .003 | 0.02 |
| P selectin | −0.12 ± 0.03 | .003 | 0.02 |
| TFF3 | −0.13 ± 0.03 | .003 | 0.02 |
| Urokinase type plasminogen activator receptor | −0.14 ± 0.04 | .005 | 0.03 |
| MCP4 | −0.08 ± 0.02 | .005 | 0.03 |
| B2M | −0.07 ± 0.02 | .005 | 0.04 |
| Thrombomodulin | −0.07 ± 0.02 | .006 | 0.04 |
| Cystatin B | −0.12 ± 0.04 | .006 | 0.04 |
| Lectin-like oxidized LDL receptor 1 | −0.20 ± 0.06 | .006 | 0.04 |
| CEACAM1 | −0.08 ± 0.02 | .007 | 0.04 |
| SHBG | −0.16 ± 0.05 | .008 | 0.05 |