Table 3.

Multivariable prediction model of incident depression during 2-year follow-up

Predictor	RC	OR	95% CI	P value
Female sex		–	–	–
Age		–	–	–
Somatic disorder		–	–	–
DM2
CHD
DM2 and CHD
History of depression		–	–	–
Baseline depression scores	0.32 p.p.i.	1.37	1.20 to 1.55	0.00
Baseline anxiety scores	0.12 p.p.i.	1.13	1.02 to 1.25	0.01
Stressful life event in past year	0.74	2.10	1.02 to 4.32	0.04
>3 chronic illnesses	0.78	2.19	1.12 to 4.25	0.02
Randomisation status I versus C	0.14	1.15	0.58 to 2.29	0.68

An OR >1 reflects a higher probability the outcome an incident depression and an OR <1 reflects a lower probability compared with the reference category. OR estimated after multiple imputation (n=25 data sets) with p value of 0.157. Linear predictor corrected after bootstrapping=−4.1147 + 0.131*Randomisation status+0.7167*>3 chronic illnesses+0.680*stressful life event in past year+0.1118*baseline anxiety scores+0.2868*baseline depression scores.

CHD, coronary heart disease; DM2, diabetes mellitus type 2; p.p.i., per point increase; RC, regression coefficient.