Table 1.
Demographic, clinical and hormonal characteristics of study population: women with polycystic ovary syndrome (PCOS) and controls
| All (n=319) |
PCOS (n=200) |
Controls (n=119) |
Mean difference | 95% CI of mean difference | P values | ||
| Lower | Upper | ||||||
| Age (years) | 27.9 (6.4) | 28.4 (5.9) | 27.2 (7.2) | 1.24 | −0.22 | 2.71 | 0.09 |
| BMI (kg/m2) | 28 (5.9) | 29 (6.3) | 26.5 (5) | 2.53 | 1.19 | 3.87 | 0.000 |
| Waist/hip ratio | 0.94 (0.09) | 0.94 (0.09) | 0.93 (0.09) | 0.0067 | −0.017 | 0.031 | 0.58 |
| Menarche (years) | 12.5 (1.4) | 12.5 (1.5) | 12.4 (1.2) | 0.12 | −0.21 | 0.45 | 0.47 |
| HOMA-IR | 3.2 (0.18) | 3.8 (0.26) | 2.1 (0.2) | 1.67 | 0.94 | 2.4 | 0.000 |
| QUICKI | 0.6 (0.006) | 0.57 (0.008) | 0.65 (.01) | −0.078 | −0.10 | −0.05 | 0.000 |
| Total adiponectin (ng/L) | 33.8 (1.4) | 28.4 (1.3) | 44.6 (2.9) | −16.25 | −21 | −10 | 0.000 |
| Albumin (g/L) | 37.3 (0.46) | 32.7 (0.46) | 45 (0.35) | −12.22 | −13.52 | −10.93 | 0.000 |
| CRP (mg/L) | 11.1 (1.1) | 15.5 (1.6) | 3.6 (0.85) | 11.89 | 7.61 | 16.17 | 0.000 |
| CRP/albumin ratio | 0.36 (0.04) | 0.53 (0.06) | 0.08 (0.02) | 0.45 | 0.29 | 0.61 | 0.000 |
| SHBG (nmol/L) | 60.1 (1.5) | 52.2 (1.4) | 72 (2.8) | −19.72 | −26.5 | −13.93 | 0.000 |
| DHEAS (nmol/L) | 6.2 (0.28) | 6.2 (0.29) | 6.3 (0.95) | −0.18 | −0.174 | 1.36 | 0.81 |
| Total testosterone (nmol/L) | 1.7 (0.06) | 1.8 (0.07) | 1.5 (0.1) | 0.23 | −0.02 | 0.49 | 0.08 |
| Bioavailable testosterone (nmol/L) | 0.49 (0.02) | 0.52 (0.03) | 0.42 (0.03) | 0.098 | 0.015 | 0.18 | 0.02 |
| Free Androgen Index | 3.4 (0.16) | 4.0 (0.22) | 2.4 (0.16) | 1.57 | 0.93 | 2.2 | 0.000 |
| Free Testosterone Index | 0.025 (0.001) | 0.029 (0.001) | 0.017 (0.001) | 0.011 | 0.007 | 0.015 | 0.000 |
Data are presented as means (SD).
BMI, body mass index; CRP, C reactive protein; HOMA-IR, homeostatic model assessment for insulin resistance; QUICKI, Quantitative Insulin Sensitivity Check Index; SHBG, sex hormone binding hormone.