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. 2018 Aug 2;8(6):419–430. doi: 10.1007/s13659-018-0180-z

Table 7.

The inhibitory effect of all compounds on rabbit platelet aggregation induced by PAF (0.4 µg/mL)a

Compound Concentration (µg/mL) Inhibition (%)b
11 c 900 84.9 ± 7.0
600 66.8 ± 3.9
300 36.4 ± 3.1
150 21.9 ± 6.6
75 10.7 ± 8.5
14 c 800 68.1 ± 12.6
600 51.2 ± 12.7
300 20.4 ± 7.1
150 10.9 ± 0.6
75 6.0 ± 2.6
15 c 900 73.3 ± 14.6
600 50.4 ± 6.7
300 33.6 ± 5.1
150 23.9 ± 9.6
75 18.3 ± 7.4
20 300 16.8 ± 6.7
25 300 17.0 ± 7.6
Ginkgolide Bd 25 90.2 ± 10.4
12.5 56.9 ± 11.2
6.25 33.9 ± 9.3
3.125 19.5 ± 9.6
1.5625 9.0 ± 5.2

aThe inhibition of other tested compounds (110, 12, 13, 1619, 2124, and 2637) was less than 10% at the concentration of 300 µg/mL

bmean ± SD, n = 3

cThe IC50 values of 11, 14, and 15 was 470.3 ± 51.6 µg/mL, 614.9 ± 113.5 µg/mL, and 579.7 ± 139.1 µg/mL, respectively

dPositive control (IC50 = 12.2 ± 2.8 µg/mL)