Table 2.
Serum oxidative stress markers | Tinnitus group (mean ± SD) | Control group (mean ± SD) | p-value |
---|---|---|---|
Native thiol (mmol/L) | 352.89 ± 48.15 | 398.61 ± 46.69 | <0.01 |
Total thiol (mmol/L) | 403.29 ± 39.15 | 431.86 ± 48.64 | 0.09 |
Disulphide (mmol/L) | 25.20 ± 13.45 | 16.63 ± 6.27 | 0.01 |
Disulphide/native thiol (%) | 7.68 ± 5.50 | 4.23 ± 1.62 | 0.01 |
Disulphide/total thiol (%) | 6.33 ± 3.60 | 3.86 ± 1.39 | <0.01 |
Native thiol/total thiol (%) | 87.35 ± 7.21 | 92.29 ± 2.77 | <0.01 |
Lipid hydroperoxide, LOOH, (μmol/L) | 5.28 ± 0.63 | 4.39 ± 0.59 | <0.01 |
TAS (mmol Trolox Equiv/L) | 1.01 ± 0.11 | 1.29 ± 0.22 | <0.01 |
TOS (μmol H2O2 equiv/L) | 14.72 ± 2.12 | 11.04 ± 1.02 | <0.01 |
OSI (arbitrary units) | 1.47 ± 0.26 | 0.88 ± 0.15 | <0.01 |
Values were expressed as mean ± standard deviation (SD). Italic values indicate statistically significant
p value is calculated by 2-tailed t-test
TAS total antioxidant status, TOS total oxidant status, OSI oxidative stress index