Changes in blood pressure, eGFR and serum uric acid concentration before and after switching from sitagliptin to linagliptin. Abbreviations are shown in the text. Data are expressed as mean ± SD. Repeated measures ANOVA with post hoc Bonferroni test was used for statistical analysis. *P < 0.05, **P < 0.01, ***P < 0.001 versus the value at switching from sitagliptin to linagliptin. #
P < 0.05, †
P < 0.01, ††
P < 0.001 versus the value at the initiation of sitagliptin