Table 7.

Safety endpoint parameters

	Baseline	Week 24	P value
Body weight (kg)	68.9 ± 14.9	68.6 ± 15.6	0.623
BMI (kg/m2)	25.8 ± 5.0	25.6 ± 5.1	0.556
CK (IU/L)	89.0 (70.5, 168.0)	99.0 (70.5, 160.0)	0.526
AST (IU/L)	26.5 ± 14.0	23.8 ± 10.2	0.056
ALT (IU/L)	24.8 ± 12.0	24.1 ± 10.7	0.594
γ-GTP (IU/L)	33.8 ± 21.7	33.6 ± 24.2	0.922
Myalgia (n%)	0 (0)	6 (13.3)	0.012

Data are expressed as mean ± SD except for CK, which is shown as median (interquartile range)

SD standard deviation, BMI body mass index, CK creatine kinase, AST aspartate aminotransaminase, ALT alanine aminotransaminase, γ-GTP gamma-glutamyltransferase