Table 1.
Effects of thyroid hormone on glucose metabolism in specific organ or cells
Organ | Effects on glucose metabolism |
---|---|
Gastrointestinal tract | Increase of mobility of gastrointestinal tract, Increased absorption of glucose |
Liver | Increase of PEPCK activity, Increase of gluconeogenesis |
Adipose tissue | Increase of lipolysis, elevation of serum free fatty acid |
Skeletal muscle | Increase of GLUT4, increase of glucose uptake |
Pancreatic beta cells | Inhibition of apoptosis, activation of growth and differentiation Increase of insulin secretion |
Pancreatic alpha cells | Increase of glucagon secretion |