Figure 1.

Schematic presentation of a nucleosome array and the variable parameters of the system. The DNA unwrapping is described by parameters U^L and U^R representing the numbers of unwrapped basepairs at the left and right ends of nucleosomes. (The U^L and U^R values are changing independently in each nucleosome.) The static histone cores are shown by the white beads and the static wrapped DNA is shown in yellow, whereas the dynamic linkers are shown as white, blue, and red tubes. In a single MC step, a dynamic linker L_i (connecting nucleosomes N_i and N_i+1) is chosen. Then, in this linker, a dimeric step is selected for modification (green arrow). Details of the fiber geometry, energy terms, and MC moves are given in Figs. S1–S3. To see this figure in color, go online.