ABCB1 |
ATP-binding cassette sub-family B member 1 |
ALL |
acute lymphoblastic leukemia |
Bcr-Abl |
breakpoint cluster region-Abelson |
Btk |
Bruton’s tyrosine kinase |
CML |
chronic myeloid leukemia |
c-Src |
cellular-sarcoma tyrosine kinase |
DIPEA |
N,N-diisopropylethylamine |
EMA |
European Medicines Agency |
FDA |
Food and Drug Admnistration |
FRET |
fluorescence resonance energy transfer |
GBM |
glioblastoma multiforme |
HRI |
hydrophobic region I |
HTS |
high-throughput screening |
NB |
neuroblastoma |
NCEs |
new chemical entities |
PDGFR |
platelet derived growth factor receptor |
Ph+
|
Philadelphia chromosome–positive |
RET |
REarranged during Transfection |
SFK |
Src family kinase |
SH |
Src homology |
STK |
serine/threonine kinase |
TK |
tyrosine kinase |
VEGFR |
vascular endothelial growth factor |