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. 2018 Aug 21;23(9):2097. doi: 10.3390/molecules23092097

Figure 6.

Figure 6

(A) The antibiotic combined assay to induce CC-resistance in the BAA-977, carrying the erm (A) inducible CC-resistance gene. The experiment was performed using the doses of CC that naturally exerted antimicrobial activity (1, 0.5, 0.25, 0.125, 0.06 mg/mL) combined with different doses of Ery (from 2 mg/mL to 0.06 mg/mL) against BAA-977. (B) The same experiment was done using the ATCC 25923 strain, lacking the resistance inducible gene. A statistical analysis (Two way ANOVA) was performed by the GraphPad Prism6 software and the p value < 0.0001 (****) showed a significant difference between the treatment with 1 mg/mL of MOR/α-CD of the resistant strain in each combined well and the untreated bacteria (0 mg/mL).