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Biosynthesis of BCAAs. The genes and enzymes are shown in italic font and in parentheses. AHAS (ilvBN) acetohydroxyacid synthase, AHAIR (ilvC) acetohydroxyacid isomeroreductase, DHAD (ilvD) dihydroxyacid dehydratase, BCAT (ilvE) branched-chain amino acid aminotransferase, IPMS (leuA) 2-isopropylmalate synthase, AspB (aspB) aspartate aminotransferase. Deletion of genes and the respective proteins are indicated by “X”.
