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Typical MRM chromatograms of aesculin (1), aesculetin (2), fraxetin (3), fraxin (4), polydatsin (5), puerarin (6). Blank plasma from six beagle dogs (A); spiked plasma samples with the analytes and IS at LLOQ level (B); spiked plasma samples with the analytes and IS at QCM (C); plasma samples from beagle dog 1 h after oral administration of the extract of L. palustre (D).
