Table 4.
Extraction recovery and matrix effect of analytes in beagle dog plasma (n = 6).
| Analytes | Spiked Concentration (ng/mL) |
Extraction Recovery | Matrix Effect | ||
|---|---|---|---|---|---|
| Mean (%) | RSD (%) | Mean (%) | RSD (%) | ||
| aesculin | 1.52 | 85.25 | 9.3 | 97.08 | 2.4 |
| 12.18 | 86.11 | 6.9 | 106.28 | 4.8 | |
| 78.00 | 91.59 | 5.2 | 100.59 | 6.4 | |
| aesculetin | 3.27 | 89.14 | 10.2 | 97.13 | 13.2 |
| 26.16 | 91.15 | 5.2 | 96.87 | 7.6 | |
| 167.3 | 87.10 | 6.9 | 100.91 | 7.0 | |
| fraxetin | 6.45 | 86.65 | 8.9 | 99.51 | 10.8 |
| 51.60 | 98.54 | 6.8 | 101.08 | 7.4 | |
| 330.2 | 88.21 | 5.2 | 106.22 | 8.1 | |
| fraxin | 3.76 | 80.10 | 5.9 | 98.66 | 8.3 |
| 30.12 | 88.58 | 6.1 | 100.39 | 5.5 | |
| 192.8 | 90.20 | 3.4 | 102.52 | 6.8 | |
| polydatin | 1.52 | 82.07 | 7.7 | 95.86 | 6.4 |
| 12.18 | 81.33 | 5.2 | 99.28 | 7.6 | |
| 78.00 | 88.24 | 3.3 | 100.23 | 5.2 | |
| IS | 260.0 | 96.81 | 5.9 | 98.47 | 8.9 |