Table 2.
Antibacterial activity.
| Compound | Diameter of Inhibition Zone in Agar Diffusion Assay (mm) (MIC) (μmol L−1) | |||||
|---|---|---|---|---|---|---|
|
B. subtilis (ATCC 6633) |
M. luteus (ATCC 10240) |
M. vaccae (DSM 43514) |
S. aureus (CCM 2524) |
P. aeruginosa (CCM 3955) |
E. coli (CCM 3954) |
|
| 5a | 13 | 14 | 15 | 15 | 15 | 12 |
| 5b | 12 | 15 | 20(>200) | 19 | 20(>200) | 0 |
| 5c | 18 | 17 | 25(50) | 18 | 16 | 0 |
| 5d | 33(50) | 22(50) | 23(25) | 18 | 15 | 0 |
| 5e | 22(>200) | 18 | 23(200) | 13 | 12 | 12 |
| 5f | 35(50) | 30(100) | 31(25) | 20(50) | 15 | 13 |
| 5g | 20(100) | 14 | 16 | 11 | 12 | 0 |
| 5h | 34(50) | 30(100) | 22(25) | 20(50) | 15 | 0 |
| 5i | 28(50) | 22(50) | 18 | 17 | 15 | 0 |
| 5j | 19 | 18 | 17 | 19 | 13 | 12 |
| 5k | 41(6.25) | 33(3.13) | 31(12.5) | 24(25) | 16 | 11 |
| 5l | 34(12.5) | 30(3.13) | 32(12.5) | 20(50) | 15 | 0 |
| 6e | 0 | 13 | 19 | 13 | 15 | 14 |
| 6f | 11 | 16 | 12 | 0 | 15 | 15 |
| 6g | 11 | 16 | 12 | 0 | 15 | 15 |
| 6h | 0 | 15 | 14 | 12 | 16 | 11 |
| 6i | 14 | 16 | 13 | 11 | 18 | 0 |
| 6j | 11 | 16 | 12 | 0 | 18 | 10 |
| 6k | 12 | 15 | 14 | 14 | 17 | 0 |
| 6l | 12 | 10 | 10 | 14 | 0 | 0 |
| 7c | 13 | 20 | 10 | 15 | 0 | 0 |
| 7d | 13 | 19 | 21(100) | 15 | 0 | 0 |
| 7e | 11 | 26(50) | 11 | 12 | 14 | 13 |
| 7f | 13 | 36(25) | 21(50) | 17 | 13 | 12 |
| 7g | 39(6.25) | 48(12.5) | 18 | 15 | 14 | 12 |
| 7h | 26(25) | 40(50) | 15 | 14 | 15 | 11 |
| 7i | 25(25) | 42(3.13) | 40(6.25) | 13 | 10 | 0 |
| 7j | 35(12.5) | 42(0.78) | 40(12.5) | 13 | 12 | 0 |
| 7k | 30(12.5) | 42(3.13) | 30(3.13) | 20(50) | 0 | 12 |
| 7l | 30(25) | 37(3.13) | 30(3.13) | 18 | 0 | 0 |
| 9t | 15 | 25(50) | 21(50) | 15 | 10 | 10 |
| 9u | 15 | 20(25) | 25(50) | 18 | 13 | 10 |
| 9w | 17 | 20(50) | 21(50) | 17 | 10 | 12 |
| 9z | 15 | 33(25) | 21(50) | 17 | 13 | 10 |
| 13 | 15 | 12 | 16 | 15 | 0 | 0 |
| 14 | 25(0.78) | 22(6.25) | 23(0.78) | 24(0.78) | 0 | 15 |
| norchelerythrine | 14 | 11 | 17 | 18 | 0 | 0 |
| isodecarine | 16 | 11 | 12 | 16 | 0 | 0 |
| NK-109 | 32(1.56) | 27(12.5) | 45(12.5) | 25(12.5) | 0 | 15 |
| chelerythrine | 30(3.13) | 26(50) | 32(3.13) | 24(6.25) | 0 | 16 |
| sanguinarine | 29(3.13) | 27(25) | 27(6.25) | 24(6.25) | 0 | 17 |
| Ciprofloxacin * | 20(7.5) | 22(0.26) | 27(0.26) | 20(15.0) | 15(3.75) | 20(7.5) |
* used as a standard.