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. 2018 Aug 27;23(9):2151. doi: 10.3390/molecules23092151

Scheme 1.

Scheme 1

The synthetic route for the preparation of the compounds (1, 2, 3ai, 4ai). Reagents and conditions: (i) 40% (w/v) sodium hydroxide, ethanol, rt, 24 h; (ii) appropriate phenylhydrazine hydrochloride derivative, CH3COOH, reflux, 8 h.