Table 3.
Comp. | IC50 (μM) | Selectivity Ratio 1 | |
---|---|---|---|
HepG2 | LO2 | ||
4a | 23.63 | 40.15 | 1.7 |
4b | 23.41 | 65.29 | 2.79 |
4c | 21.93 | 53.03 | 2.42 |
4d | 36.34 | 248.39 | 6.84 |
4e | 31.83 | 54 | 1.70 |
4f | 3.03 | 49.47 | 16.33 |
4g | 2.86 | 58.92 | 20.60 |
4h | 20.74 | 82.34 | 3.97 |
4i | 27.87 | 75.57 | 2.71 |
4j | 12.58 | 36.37 | 2.89 |
4k | 21.19 | 51.99 | 2.45 |
4l | 17.29 | 78.6 | 4.55 |
4m | 18.29 | 48.42 | 2.65 |
4n | 7.9 | 49.9 | 6.32 |
TSA | 23.85 | 65.29 | 2.74 |
1 IC50 (LO2)/IC50 (HepG2).