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. 2018 Oct 10;140(44):14789–14798. doi: 10.1021/jacs.8b08311

Table 2. Kinetic Parameters for Surface-Seeded PrPa.

seed type ke (M–1 s–1) kf (s–1)b kekf (M–1 s–2)b PK-sen to PK-res conversion half-time
soluble seed 3.39 ± 0.04 × 104 ≥5 × 10–9 ≥0.00017 0.25 h
insoluble seed 1 × 104 ≥1.6 × 10–8 ≥0.00016  
a

ke elongation rate constant; kf fragmentation rate constant. The errors represent uncertainties of the fitting parameters given the dataset.

b

Measured as the slowest value.