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Sinomenine inhibited morphine-induced conditioned place preference in mice. (A) Schematic protocol of the conditioned place preference testing; (B) The time spent in the white compartment in preconditioning and postconditioning phases (n = 8). ## p < 0.01 vs. control, ΔΔ p < 0.01 vs. mor, * p < 0.05 vs. mor + Sino. Mor, morphine; Sino, sinomenine; NMDA, n-methyl-d-aspartate.
