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. 2018 Sep 17;23(9):2370. doi: 10.3390/molecules23092370

Figure 2.

Figure 2

Sinomenine inhibited the expressions of p-NMDAR1/NMDAR1, p-CAMKII/CAMKII, and p-CREB/CREB in the hippocampus of morphine-dependent mice. (A–D) Immunohistochemistry analysis was used to quantify the expression levels of p-NMDAR1 and NMDAR1 in the hippocampus of morphine-dependent mice (n = 3); (E–J) Western blotting analysis was used to quantify the expression levels of p-NMDAR1/NMDAR1, p-CAMKII/CAMKII, and p-CREB/CREB in the hippocampus (n = 3). ## p < 0.01 vs. control; Δ p < 0.05, ΔΔ p < 0.01 vs. mor; * p < 0.05 vs. Sino.