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Folic acid inhibited the cell viability of RVECs. The cells (4000 per/well) were treated with HG or various concentrations of folic acid for 72 h. The abbreviation HG represents high glucose, i.e., the cells were cultured in a medium with a glucose concentration at 25 mM. The effect of folic acid (0.1–0.0001 μg/mL) on RVECs viability was assessed by CCK-8 assay. The data was presented as means ± SD (n = 5–6). * p < 0.05, ** p < 0.01, compared with HG-treated cells.
