Table 3.
Univariable and multivariable odds ratios (OR) and 95% confidence intervals (95% CI) for factors associated with non-adherence to tuberculosis (TB) treatment‡.
Univariable |
Multivariable‡ |
|||||||
---|---|---|---|---|---|---|---|---|
Risk factors | OR | 95% CI | aOR* | 95% CI | ||||
Individual characteristic | ||||||||
Age < 35yrs | 2.2 | 1.2 | - | 3.9 | 3.1 | 1.5 | - | 6.6 |
Papuan ethnicity | 2.1 | 1.2 | - | 3.8 | NS | |||
At risk for alcoholism | 3.0 | 1.2 | - | 7.3 | NS | |||
Family characteristics | ||||||||
>1 person per 10m2 in household | 2.0 | 1.1 | - | 3.4 | NS | |||
Having a household member treated for TB | 2.2 | 1.2 | - | 3.9 | 2.5 | 1.2 | - | 5.2 |
Access and mobility | ||||||||
Moved residence in the last year | 7.5 | 2.0 | - | 28 | 9.6 | 2.2 | - | 42 |
Distance/travel costs perceived as problem | 12.7 | 2.7 | - | 60 | 10.2 | 1.7 | - | 60 |
Finds costs of TB treatment too high | 2.1 | 1.1 | - | 3.9 | NS | |||
Treatment experience | ||||||||
Received loose drugs (instead of fixed dose combination) | 4.4 | 1.7 | - | 12 | 3.8 | 1.2 | - | 12 |
Having side effect from TB treatment | 2.1 | 1.2 | - | 3.7 | NS | |||
Has not received education about TB | 3.8 | 1.5 | - | 9.7 | 3.5 | 1.0 | - | 12 |
Patient knowledge | ||||||||
Does not know the cause of TB | 3.2 | 1.8 | - | 5.9 | 2.4 | 1.1 | - | 5.4 |
Does not know how TB is transmitted | 4.5 | 2.5 | - | 8.0 | 3.8 | 1.8 | - | 7.8 |
Thinks that TB cannot be cured | 3.5 | 2.9 | - | 4.3 | ||||
Unaware about the duration of a full TB treatment course | 6.3 | 1.9 | - | 21 | NS | |||
Unaware about the consequences of incomplete TB treatment | 6.9 | 2.6 | - | 19 | 10.3 | 3.1 | - | 34 |
‡NS: not statistically significant in multivariable model (applying backward stepwise logistic regression; retaining all variables with a p-value of <0.05 in the model)
*Adjusted for all other variables with an adjusted OR in this table.
‡The total subject analyzed for the final model were 262 (79/81 cases, and 183/183 controls).