Table 3.

Possible effects of C. pubescens in metabolic disturbances.

Host	Effects	Extract/Doses	Reference
Antioxidant activity assay	Exhibited high antioxidant activity	Leaf extract	[88]
		Root, stem, leaf and fruit extracts	[89]
Antioxidant activity assay and In vitro	Exhibited high antioxidant activity together with antitumoral activity in the human tumor lineage in vitro assay	Fruit extracts	[91]
Rats	Reduced the number of monocytes (anti-inflammatory potential) Decreased plasma levels of hepatic enzymes (ALT and AST) withour renal toxicity	Leaf extract (250 and 500 mg/kg)	[92]

Principal studies of C. pubescens with possible effects in metabolic disorders accomplished in animal models (in vivo) and to evaluate its antioxidant activity.