TABLE 1.

Biodistribution of ¹⁷⁷Lu-DOTA-EB-TATE (SUV, n = 5) and ¹⁷⁷Lu-DOTATATE (SUV, n = 3) in Patients with Advanced NETs

	177Lu-DOTA-EB-TATE				177Lu-DOTA-TATE
Organ	2 h	24 h	72 h	168 h	1 h	3 h	24 h	72 h
Blood	3.39 ± 1.17	1.75 ± 0.58	1.29 ± 0.44	0.94 ± 0.30	0.17 ± 0.04	0.15 ± 0.02	0.09 ± 0.03	0.03 ± 0.00
Lung	0.41 ± 0.14	0.25 ± 0.09	0.21 ± 0.06	0.14 ± 0.06	0.07 ± 0.02	0.06 ± 0.01	0.05 ± 0.01	0.04 ± 0.01
Liver	1.82 ± 0.73	1.39 ± 0.46	1.27 ± 0.45	1.07 ± 0.41	1.39 ± 0.12	1.25 ± 0.18	0.94 ± 0.09	0.85 ± 0.20
Spleen	3.24 ± 1.50	3.34 ± 1.97	3.54 ± 2.67	3.57 ± 2.97	4.21 ± 0.22	3.93 ± 0.32	3.42 ± 0.52	3.70 ± 0.74
Pancreas	2.23 ± 0.68	1.62 ± 0.45	1.18 ± 0.32	0.98 ± 0.21	0.85 ± 0.23	0.76 ± 0.18	0.57 ± 0.25	0.60 ± 0.22
Kidneys	2.67 ± 0.89	3.03 ± 1.22	3.20 ± 1.86	2.47 ± 1.49	1.78 ± 0.38	1.54 ± 0.22	1.14 ± 0.19	1.13 ± 0.15
Muscle	0.11 ± 0.03	0.17 ± 0.03	0.14 ± 0.04	0.10 ± 0.03	0.09 ± 0.02	0.08 ± 0.03	0.07 ± 0.02	0.07 ± 0.02

Data are mean ± SD.