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. 2018 Nov 8;10:140. doi: 10.1186/s13148-018-0572-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Perceived facial ageing is associated with all-cause mortality, but not with DNA methylation signatures trained on perceived ageing. a Kaplan-Meier plots depict survival rates of LBC1921 participants stratified by the median perceived age in facial images (face-age). b Alternatively, the participants were stratified by mean age predictions based on an algorithm of 32 CpGs that was trained on face-age of the LBC1921 (DNAm_face-age). c The results with this algorithm did not replicate in the independent LBC1936 cohort