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. 2018 Nov 8;16:77. doi: 10.1186/s12964-018-0291-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — (a/c) HCC827 and H1975 cells were transfected as indicated. 48 h post transfection, whole cell lysates were harvested and levels of cleaved PARP, cleaved caspase 9, cleaved caspase 3, and BCL-2 were assessed by immuno-blotting using anti-cleaved PARP, anti-caspase 9, anti-cleaved caspase 3, anti-BCL-2, in addition to α-tubulin, as a loading control. (b/d) HCC827 and H1975 cells were transfected as indicated. Caspase-3/7 activity levels were assessed 48 h post-transfection. ** p < 0.01, *** p < 0.001