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. 2018 Nov 8;9:305. doi: 10.1186/s13287-018-1060-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Angiogenic potential of autophagy. Starvation-induced autophagy triggers cell migration and in vitro angiogenesis by activating of VEGF and AKT protein on ECs. AGGF1-induced autophagy is a candidate for coronary artery disease and myocardial infarction treatment. Chemerin, a novel adipose tissue cytokine, also has a stimulatory effect on retinal endothelial cells angiogenesis by promoting autophagy activity and expression of the autophagy-related proteins LC3 and Beclin-1 increased during chemerin-induced migration and tubular formation