Table 2.
Prevalence of Pvdhfr, Pvdhps, Pvmdr1, and Pvk12 allelic variants in Nouakchott and Atar, Mauritania
| Gene | Allelic varianta | Nouakchott n/N (%) | Atar n/N (%) |
|---|---|---|---|
| Pvdhfr | IPFSTSI (wild-type) | 126/154 (81.8) | 44/45 (97.8) |
| IPFRMSI | 28/154 (18.2) | 0 | |
| IPFSTNI | 0 | 1/45 (2.2) | |
| Pvdhps | SAKAV (wild-type) | 93/93 (100) | 37/37 (100) |
| Pvmdr1 | YF (wild-type) | 110/115 (95.7) | 76/79 (96.2) |
| FF | 5/115 (4.3) | 1/79 (1.3) | |
| YL | 0 | 2/79 (2.5) | |
| Pvk12 | V552 (wild-type allele) | 59/59 (100) | 48/48 (100) |
| 552I | 0 | 0 |
n number of isolates with the given allelic variant N total number of isolates analysed
aAllelic variants are based on the following codons: 13, 33, 57, 58, 61, 117, and 174 for Pvdhfr; 382, 383, 512, 553, and 585 for Pvdhps; and 976 and 1076 for Pvmdr1. The amino acid substitution V552I in Pvk12 was suggested to be a potential marker for artemisinin-resistant P. vivax in Cambodia [39]