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. 2018 Nov 5;11:7805–7820. doi: 10.2147/OTT.S170829

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© 2018 Wu et al. This work is published and licensed by Dove Medical Press Limited

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Rab18 regulates invasion, migration, and adhesion.

Notes: (A) Matrigel invasion assay demonstrated that Rab18 overexpression upregulated invading cell number in SNU-1 cells while Rab18 depletion downregulated invading cell number in AGS cells. (B) Wound healing assay demonstrated that Rab18 overexpression facilitated cell migration in SNU-1 cells while Rab18 depletion inhibited AGS cell migration. (C) Cell adhesion assay demonstrated that Rab18 overexpression downregulated cell adhesion in SNU-1 cells while Rab18 depletion increased the number of adherent AGS cells. *P<0.05.

Rab18 regulates invasion, migration, and adhesion.

Notes: (A) Matrigel invasion assay demonstrated that Rab18 overexpression upregulated invading cell number in SNU-1 cells while Rab18 depletion downregulated invading cell number in AGS cells. (B) Wound healing assay demonstrated that Rab18 overexpression facilitated cell migration in SNU-1 cells while Rab18 depletion inhibited AGS cell migration. (C) Cell adhesion assay demonstrated that Rab18 overexpression downregulated cell adhesion in SNU-1 cells while Rab18 depletion increased the number of adherent AGS cells. *P<0.05.