Table 4.
Accuracy data of NLR for detecting COPD global and bacterial infection exacerbation
| Author, year | Cut-off | Sensitivity (%) | Specificity (%) | AUC (95% CI) |
|---|---|---|---|---|
| Kurtipek et al, 20159,a | 3.30 | 87 | 82 | 0.88 (NS) |
| Tanrıverdi et al, 201536,b | 11.50 | 61 | 52 | 0.58 (0.45–0.71) |
| Taylan et al, 201510,a | 3.29 | 80.80 | 77.70 | 0.89 (0.84–0.94) |
| Bilir et al, 201623,a | 3.35 | 69 | 59 | 0.68 (0.63–0.73) |
| In et al, 201624,a | 3.34 | 78.70 | 73.20 | 0.86 (0.79–0.93) |
| van de Geijn et al, 201632,b | 4.52 | 91 | 46 | 0.75 (0.60–0.91) |
| Yousef and Alkhiary, 201726,a | 3.12 | 86.70 | 76.70 | 0.88 (0.90–1.00) |
| Mohamed-Hussein et al, 201734,a | 1.50 | 93 | 90 | 0.68 (0.54–0.81) |
| Farah et al, 201728,b | 7.30 | 76.80 | 73.10 | 0.79 (NS) |
| Acartürk et al, 201735,a | 3.54 | 78 | 69 | – |
Notes:
a
NLR for detecting COPD global exacerbation
b
NLR for detecting COPD bacterial infection exacerbation.
Abbreviations: AUC, area under the curve; NLR, neutrophil-to-lymphocyte ratio; NS, not specified.