Table 2. Evaluation of Serious Adverse Reactions (SARs).

SAR severity	Comments
Unimportant	No damage, no risk, the patient is not informed as there is no risk of damage
Non-severe	Mild clinical/psychological consequences
	There is no hospitalization
	No long-term consequences/disabilities expected
Severe	Hospitalization or prolongation of hospitalization or permanent or significant disability or incapability
	Intervention for permanent damage exclusion
	Sign of serious transmissible disease
	Birth of a child with severe genetic disease after ART with germ cells or embryo from donor
Life-threatening	Notable intervention to prevent death
	Evidence of life-threatening transmissible disease
	Birth of a child with life-threatening genetic disease after ART with germ cells or embryo from donor
Death	Death

Source: ARTHIQS [14].