Table 3.
Differential exon usage (DEU) between current and former smokers. Significant DEU is defined as an adjusted p-value <0.05 from limma exon-based T statistic and DEXseq p-value <0.05.Gene-based P value is unadjusted from limma differential expression analysis
| Ensembl Exon ID | Gene Symbol | Limma Adjusted P value | DEXseq P value | Gene-based P value | Transcripts Containing Exon | Exon Number in Transcript |
|---|---|---|---|---|---|---|
| ENSE00001810132 | EPS15 | 4.00E-02 | 2.00E-02 | 8.16E-01 | ENST00000478657 | first |
| ENSE00002071373 | GALNT7 | 2.22E-03 | 1.66E-06 | 1.30E-01 | ENST00000502407 | first |
| ENSE00001444573 | SASH1a | 1.80E-09 | 2.39E-03 | 4.22E-21 | ENST00000367467 | last |
| ENSE00001400828 | AREL1 | 1.27E-02 | 1.18E-03 | 9.98E-01 | ENST00000356357 | last |
| ENSE00001444981 | UTRN | 5.72E-16 | 8.82E-02 | 1.75E-01 | ENST00000367545 | last |
| ENSE00001635177 | MAN1A2 | 4.00E-03 | 3.25E-02 | 9.48E-03 | ENST00000356554 | second |
| ENSE00001231507 | LRRN3a | 3.23E-10 | 4.69E-04 | 4.19E-36 | ENST00000308478 | first |
| ENSE00001175333 | ERAP1 | 7.87E-12 | 1.27E-03 | 4.27E-01 | ENST00000296754 | first |
| ENSE00001641703 | ERAP1 | 1.19E-06 | 3.63E-03 | 4.27E-01 | ENST00000443439 | first |
aDifferentially expressed gene