Table 3. Effect of baseline total body fat on Ranke’s Prediction model for the first-year height response in SGA children.
Models | B | 95% CI | P value | Partial Correlation |
Collinearity (Tolerance) |
R2 | P value (R2 change) |
|
---|---|---|---|---|---|---|---|---|
1 | Constant | 13.7 | 11.5, 15.8 | <0.0001 | ||||
Age (year) | -0.31 | -0.54, -0.09 | 0.008 | -0.30 | 0.97 | |||
Midparental height (SDS) | 0.46 | 0.07, 0.85 | 0.022 | 0.26 | 0.96 | |||
Weight at baseline (SDS) | 0.12 | -0.26, 0.50 | 0.52 | 0.07 | 0.93 | 0.15 | 0.008 | |
2 | Constant | 13.04 | 11.1, 15.0 | <0.0001 | ||||
Age (year) | -0.29 | -0.50, -0.08 | 0.008 | -0.31 | 0.97 | |||
Midparental height (SDS) | 0.47 | 0.11, 0.84 | 0.012 | 0.29 | 0.96 | |||
Weight at baseline (SDS) | -0.04 | -0.40, 0.33 | 0.84 | -0.02 | 0.88 | |||
Baseline total body fat % (z-score)* | 0.61 | 0.28, 0.95 | <0.0001 | 0.39 | 0.94 | 0.27 | 0.001 | |
3 | Constant | 10.9 | 8.36, 13.5 | <0.0001 | ||||
Age (year) | -0.19 | -0.41, 0.03 | 0.096 | -0.19 | 0.85 | |||
Midparental height (SDS) | 0.45 | 0.10, 0.79 | 0.012 | 0.28 | 0.95 | |||
Weight at baseline (SDS) | -0.13 | -0.49, 0.23 | 0.48 | -0.08 | 0.83 | |||
Baseline total body fat % (z-score)* | 0.59 | 0.26, 0.92 | 0.001 | 0.38 | 0.91 | |||
Delta IGF-1 SDS (0 to 1-yr) | 0.30 | 0.07, 0.54 | 0.013 | 0.28 | 0.82 | 0.33 | 0.013 |
within cohort z-scores for total body fat percentage at baseline adjusted for age, gender and type of scanner (z-scorec) Dependent Variable: Height velocity (cm/year); B, unstandardized coefficient; CI, confidence interval
Model 1: Ranke’s Model for prediction of first-year height velocity in SGA children; Growth Hormone dose is not included in the model as a fixed dose was used in the study
Model 2: The effect of total body fat percentage on Ranke’s Prediction Model
Model 3: Effect of the addition of change in IGF-I SDS (0 to 1-year)