Table 4. Associations between multiallele scores for insulin sensitivity and body composition^#.

	Effect size per allele (B)	95 % CI	P value*
Baseline
BMI (SDS)	-0.13	-0.26, -0.01	0.040
Body fat (%)	-0.49	-0.97, -0.01	0.047
Limb fat (%)	-0.81	-1.62, 0.00	0.049
Arm fat (%)	-1.19	-2.31, -0.06	0.038
Leg fat (%)	-0.76	-1.55, 0.03	0.060
Trunk fat (%)	-0.33	-0.77, 0.12	0.16
Trunk-limb fat ratio	0.01	-0.01, 0.03	0.49
1-year
BMI (SDS)	-0.07	-0.22, 0.09	0.40
Body fat (%)	-0.39	-0.81, 0.02	0.064
Limb fat (%)	-0.81	-1.49, -0.13	0.020
Arm fat (%)	-1.04	-1.95, -0.13	0.026
Leg fat (%)	-0.59	-1.27, 0.09	0.087
Trunk fat (%)	-0.03	-0.43, 0.37	0.88
Trunk-limb fat ratio	0.04	0.01, 0.08	0.008
Changes from baseline to 1-year
Delta body fat (%)	0.31	0.10, 0.51	0.004
Delta limb fat (%)	0.28	-0.11, 0.68	0.16
Delta arm fat (%)	0.18	-0.41, 0.78	0.54
Delta leg fat (%)	0.27	-0.16, 0.70	0.22
Delta trunk fat (%)	0.38	0.16, 0.59	0.001
Delta trunk-limb fat ratio	0.03	0.01, 0.05	0.003

^#higher scores associated with lower insulin sensitivity; B, unstandardized coefficient; CI, confidence interval

^*P-values and B are derived from regression models with age and gender as covariants